Physiological and Psychological Stress of Microwave Radiation-Induced Cardiac Injury in Rats
Abstract
Overview
Electromagnetic waves are frequently utilized in military and civilian sectors, exposing certain populations to long-term and high-power radiation, potentially posing significant health hazards.
Objective
This study aimed to simulate the occupational environment of workers exposed to special electromagnetic radiation to elucidate the stress response and cardiac damages caused by such radiation.
Methodology
- The myocardial structure was examined using optical and electron microscopes.
- Various techniques such as flow cytometry, microplate readers, and radioimmunoassay were employed to assess mitochondrial function, oxidative stress, and stress hormones, respectively.
- Heart rate variability was analyzed using a physiological recorder.
Findings
Microwave radiation of 30 mW/cm2 for 35 minutes induced physiological and psychological stress in rats, manifesting as:
- Disorganized and fragmented myocardial fibers.
- Severe mitochondrial cavitation and dysfunction.
- Increased oxidative stress and stress hormones in serum.
- Serious alterations in heart rate variability (HRV).
- Observable anxiety, depression, and reduced exercise capacity in open field experiments.
Increased levels of proteins associated with stress response pathways were detected, implicating the JNK pathway in the observed injuries.
Conclusion
This study highlights the potential severe physiological and psychological impacts of long-term and high-power exposure to microwave radiation in occupational settings, suggesting significant health risks and the urgent need for protective strategies.