Suppression of Glucocorticoid Response in Stressed Mice Using 50 Hz Electric Field According to Immobilization Degree and Posture

Abstract

Overview

This study explores the biological impacts of extremely low-frequency (ELF) electric fields on stress responses in mice. The research focuses on the effects of these fields when mice are subjected to different degrees of immobilization and positions.

Findings

• Mice were immobilized and exposed to ELF electric fields; blood samples were then collected to measure plasma glucocorticoids.
• The study found that ELF electric fields can reduce glucocorticoid levels elevated due to stress, with variations depending on the mouse's posture and the intensity of the immobilization.
• Effectiveness was noted in moderately and mildly stressed mice but not in severely immobilized subjects.

Conclusion

The research underscores the importance of ELF electric fields in modulating stress responses in mice and emphasizes the necessity to adjust stress levels accurately to ensure reproducible outcomes. The findings might have implications for understanding the biological risks and potential medical applications of ELF electric fields.