Physiological and Psychological Stress of Microwave Radiation-Induced Cardiac Injury in Rats

Abstract

Overview

Electromagnetic waves, commonly utilized in military and civilian sectors, may expose certain populations to long-term and high-power radiation, presenting significant health risks. This study explores the physiological and psychological impacts of such exposure on rats, aiming to simulate the environment of workers in electromagnetic radiation-prone occupations, and guide the scope of research on electromagnetic field (EMF) protective measures.

Findings

• Exposure to 30 mW/cm² S-band microwave radiation for 35 minutes caused notable cardiac injuries in rats, evidenced by myocardial structure disorganization and oxidative stress.
• Significant alterations in heart rate variability (HRV) and increased stress hormones were observed, along with anxiety and depression symptoms in open field experiments suggesting psychological stress.
• Increased expression of stress and inflammation markers such as JNK, p-JNK, HSF1, and NFATc4 highlights the molecular pathways potentially involved in injury mechanisms.

Conclusion

The combination of thermal and non-thermal effects from long-term, high-power microwave radiation exposure potentially leads to cardiac injuries. The study underlines critical insights for developing protective strategies for workers in similar environments and reinforces the importance of regulating exposure durations and intervals.