Physiological and Psychological Stress of Microwave Radiation-Induced Cardiac Injury in Rats

Authors: Li D, Xu X, Yin Y, Yao B, Dong J, Zhao L, Wang H, Wang H, Zhang J, Peng R.

Year: 2023

Category: Molecular Sciences

Journal: International Journal of Molecular Sciences

Institution: International Journal of Molecular Sciences

DOI: 10.3390/ijms24076237

URL: https://www.mdpi.com/1422-0067/24/7/6237

Abstract

Abstract Summary

Overview

Electromagnetic waves, common in military and civilian uses, might expose certain populations to long-term, high-power risks posing substantial health hazards. This research aims to simulate the working environment of those in occupations exposed to special electromagnetic radiations to explore the stress responses and cardiac injuries engendered.

Methodology

  • Observation of myocardial structure using optical and electron microscopes.
  • Detection of mitochondrial function and oxidative-stress markers.
  • Analysis of serum stress hormones and heart rate variability (HRV).
  • Behavioral assessments through an open field experiment.
  • Molecular analysis using Western blot and immunofluorescence.

Findings

Microwave radiation at 30 mW/cm2 and 2.856 GHz led to significant physiological and psychological stress, evidenced by myocardial fiber disorganization, mitochondrial dysfunction, oxidative stress, and altered heart rate variability. Additionally, affected rats showed symptoms of anxiety, depression, and reduced physical activity.

Conclusion

The study highlights the severe impacts of microwave radiation on cardiac health and stress levels, providing key insights into the mechanisms of radiation-induced injuries and the potential pathways for future research on radiation protection strategies.

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