Intermittent ELF-MF Induce an Amplitude-Window Effect on Umbilical Cord Blood Lymphocytes
Abstract
Overview
This study revisits the impact of extremely low frequency (ELF) magnetic fields (MF) on umbilical cord blood lymphocytes (UCBL), extending previous investigations into magnetic field amplitude effects.
Findings
- UCBLs were exposed to various MF amplitudes ranging from 3 µT to 12 µT for 72 hours.
- The exposure was conducted using a triangular signal at 7.8 Hz with alternating cycles of 250 seconds on and 250 seconds off.
- Results from flow cytometry showed no significant change in early apoptotic, late apoptotic/necrotic cells, or reactive oxygen species production. However, a decrease in viable cell percentages was observed at 6.5 µT and 12 µT.
Conclusion
The study deduces an amplitude window of 6 µT to 13 µT, within which ELF-MF can decrease the viability of cells, indicating sensitivity to specific MF amplitudes.