Investigation of Fetuin-A pathway in diabetes mellitus formation in rats exposed to ELF magnetic fields

Abstract

Overview

As the presence of technological devices increases, so does human exposure to environmental electromagnetic fields, which raises concerns about health risks, particularly in relation to diseases like cancer and diabetes.

Study Design

This study investigates the involvement of the Fetuin-A pathway in the formation of diabetes mellitus among rats exposed to extremely low frequency (ELF) magnetic fields. Divided into three groups, each containing 12 rats, differing levels of ELF exposure were used:

• The first experimental group was exposed to a 50 Hz ELF magnetic field of 0.4 mT for 6 hours daily over a span of 5 days.
• The second experimental group received the same exposure for 10 days.
• The control group was not exposed to any magnetic field.

Following the exposure period, blood collections for lab analysis were conducted.

Findings

Statistical analysis revealed significant increases in glucose, HbA1c, and Hba1 IFCC values among the rats exposed to ELF magnetic fields compared to the control group. Critically, levels of Fetuin-A also increased significantly in exposed groups, suggesting possible implications for the onset of Type 3 diabetes.

Conclusion

The results support concerns that exposure to ELF magnetic fields could be linked to an increased risk of developing diabetes by influencing biological pathways specific to Fetuin-A and glucose level management in organisms.