Investigation of Fetuin-A pathway in diabetes mellitus formation in rats exposed to ELF magnetic fields

Authors: Sert C, Delin M, Eren MA, Çakmak Y

Year: 2022

Category: Biomedical Research

Journal: Electromagn Biol Med

DOI: 10.1080/15368378.2022.2117189

URL: https://pubmed.ncbi.nlm.nih.gov/36073511/

Abstract

Overview

The increasing presence of technological devices has escalated the exposure to environmental electromagnetic fields, which is presumed to elevate risks of serious health conditions such as cancer and diabetes.

Methodology

  • Rats were divided into three groups, each consisting of 12 rats.
  • The first group was exposed to a 50 Hz ELF magnetic field at 0.4 mT for 6 hours daily over 5 days.
  • The second group underwent the same exposure for 10 days.
  • The control group was not subjected to any magnetic field exposure.

Findings

Blood samples were collected from each group after exposure for laboratory analysis and statistical comparison.

  • No significant differences were observed in transaminases, lipid profiles, and C-Peptide levels.
  • Similarly, no significant variations were found in insulin, urea, creatinine, and electrolytes.
  • Significant increases were detected in glucose, HbA1c, and Hba1 IFCC values (p < .001) amongst the exposed groups in comparison to the control.
  • Moreover, a notable elevation in Fetuin-A levels was recorded (p < .05) in exposed rats.

Conclusion

These findings suggest that exposure to ELF magnetic fields increases specific markers that are potentially linked to the development of Type 3 diabetes, identifying a significant health risk.

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