Effects of Antioxidant Vitamins on Proinflammatory Cytokines and Biochemical Parameters of Power Plant Workers: Double-Blind Randomized Controlled Clinical Trial

Authors: Majid Bagheri Hosseinabadi, Narges Khanjani, Pirasteh Norouzi, Ali Faghihi-Zarandi, Davood Darban-Sarokhalil, Seyed Sajjad Khoramrooz, Seyed Reza Mirbadie, Mehdi Mirzaii

Year: 2020 Sep 15

Category: Clinical Trial, Epidemiology

Journal: Bioelectromagnetics

Institution: Bioelectromagnetics

DOI: 10.1002/bem.22294

URL: https://pubmed.ncbi.nlm.nih.gov/32931612/

Abstract

Overview

This study explores the impact of long-term exposure to extremely low-frequency magnetic fields (ELF-MFs) on power plant workers and assesses the mitigative role of antioxidant vitamins on health risks.

Methodology

In a double-blind randomized controlled study, 91 power plant workers subjected to ELF-MFs were divided into four groups. These groups received different daily doses of vitamin E and C across three months, with their health outcomes compared against a control group not receiving supplements.

Findings

  • Significant decreases in proinflammatory cytokines such as IL-6, IL-1β, and TNF-α were observed in groups consuming vitamins.
  • Improvements were noted in HDL cholesterol and triglyceride levels post-intervention.

Conclusion

Consumption of antioxidant vitamins appears to protect against the increase of proinflammatory cytokines triggered by ELF-MF exposure, suggesting a potential protective strategy for workers in high-risk electromagnetic environments.

ELF magnetic fields antioxidant vitamins proinflammatory cytokines biochemical parameters randomized controlled trial
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