Effects of extremely low-frequency (50 Hz) electromagnetic fields on vital organs of adult Wistar rats and viability of mouse fibroblast cells

Authors: Tekam CKS, Majumdar S, Kumari P, Prajapati SK, Sahi AK, Singh R, Krishnamurthy S, Mahto SK

Year: 2024

Category: Radiation Protection Dosimetry

Journal: Radiat Prot Dosimetry

DOI: 10.1093/rpd/ncae220

URL: https://pubmed.ncbi.nlm.nih.gov/39656829/

Abstract

Overview

This study evaluates the health impacts of periodic exposure to extremely low-frequency pulsed electromagnetic fields (ELF-PEMF) on both in vivo (adult Wistar rats) and in vitro (mouse fibroblast RFP-L929 cells) models. The exposure was set at 1-3 mT, 50 Hz, for less than one hour per day.

Findings

  • No significant changes were observed in cell proliferation and morphology in RFP-L929 cells.
  • There were mild increases in aspartate aminotransferases, alanine aminotransferases, total bilirubin, serum creatinine, and creatine kinase-myocardial band levels among the ELF-PEMF exposed groups.
  • However, no significant changes were found in tissue structure and morphologies upon histological examination.

Conclusion

The research reveals that a 20-minute exposure with a 4-hour gap to 50 Hz ELF-PEMF does not cause destructive changes in RFP-L929 cells nor significant changes in the morphology and physiological parameters of adult Wistar rats. While there were minor alterations in biochemical parameters, these were insufficient to induce pathological changes in the studied organ and tissues.

ELF-PEMF electromagnetic fields Wistar rats mouse fibroblast cells biochemical parameters histological examination in vivo and in vitro
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