Effects of different mobile phone UMTS signals on DNA, apoptosis and oxidative stress in human lymphocytes

Authors: Sachin Gulati, Pavol Kosik, Matus Durdik, Milan Skorvaga, Lukas Jakl, Eva Markova, Igor Belyaev

Year: 2020 Dec

Category: Environmental Science

Journal: Environ Pollut

DOI: 10.1016/j.envpol.2020.115632

URL: https://pubmed.ncbi.nlm.nih.gov/33254645/

Abstract

Overview

Different scientific reports have suggested a link between exposure to radiofrequency radiation (RF) from mobile communications and the induction of reactive oxygen species (ROS) and DNA damage, though findings have been mixed.

Findings

  • For the first time, the study comparatively analyzed genotoxic effects of UMTS signals at different frequency channels used by 3G mobile phones (1923, 1947.47, and 1977 MHz).
  • Genotoxicity was assessed through several methods, including ROS induction, DNA damage, gene mutation analysis, and apoptosis detection.
  • No effects of RF exposure were noted on ROS, apoptosis, preleukemic fusion genes (PFG), and mutations in the TP53 gene regardless of the UMTS frequency.
  • Statistically significant DNA damage was observed at frequencies, notably at 1977 MHz.

Conclusion

While some frequencies of UMTS signals may induce DNA damage, no broader genotoxic effects were apparent according to the study's findings. The research supports the need for further targeted investigations to ensure prolonged exposure to RF from mobile communications does not pose health risks.

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