Abstract

Overview

Exploring the impact of microwave exposure on cardiac health has increasingly drawn attention both domestically and internationally. However, the specific biological effects attributable to varying doses and frequency bands remain obscure.

Findings

This study focuses on investigating the harmful effects of composite S-band and X-band microwave exposure on the cardiac structure and function of Wistar rats. Techniques such as ECG and automatic biochemical analysis were employed to assess these effects at multiple time points post-exposure. Observations of myocardial structure alterations and the expression levels of Connexin43 (Cx43) were pivotal in understanding the changes induced by the exposure.

• Dose- and frequency-dependent increases in heart rate and changes in ECG wave amplitudes were noted.
• A significant rise in myocardial enzyme levels in serum was observed, indicative of cardiac injury.
• Decreased expression and disordered distribution of Cx43 were strongly linked to abnormal cardiac electrical conduction.

Conclusion

The results elucidate the potential mechanisms underlying cardiac dysfunctions due to S- and X-band microwave exposures, particularly emphasizing the role of decreased and disordered Cx43 expression.