Behavioural phenotypes in mice after prenatal and early postnatal exposure to intermediate frequency magnetic fields

Authors: Kumari K, Koivisto H, Myles C, Jonne N, Matti V, Heikki T, Jukka J

Year: 2017 Dec 22

Category: Environmental Research

Journal: Environ Res

DOI: 10.1016/j.envres.2017.12.013

URL: https://www.ncbi.nlm.nih.gov/pubmed/29276976

Abstract

Overview

Electromagnetic fields (EMFs) are prevalent in the environment, heightened by modern technologies. This study focuses on investigating cognitive and behavioural impacts of intermediate frequency magnetic fields (IF MFs) on mice exposed during prenatal and early postnatal periods.

Methodology

  • Pregnant mice were exposed to IF MFs at frequencies of 7.5kHz at two intensity levels, 12 and 120μT, from mating until the weaning of pups.
  • Sham exposed pregnant mice served as a control group.

Findings

  • No significant differences were noted in body weight development between groups.
  • Several behavioral and cognitive tests revealed no changes linked to MF exposure, with exceptions in specific motor tasks not showing dose-dependent effects, hence considered likely random variations.
  • A histopathological examination showed no impact of IF MF exposure on astroglial reactivity or hippocampal neurogenesis.

Conclusion

The study indicates the intermediate frequency magnetic fields used did not significantly impact spatial learning, memory, or tissue histology in mice. While two isolated findings were noted, they are not internally consistent and likely represent random variations unrelated to MF exposure. It's crucial to recognize the potential for electromagnetic fields to influence health as human exposure to such environments increases.

electromagnetic fields intermediate frequency mouse model prenatal exposure cognitive effects behavioural study neurodevelopment
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