Abstract

Overview of the Study

The molecular mechanism of the microwave nonthermal effect remains elusive. This research utilized molecular dynamics simulations to explore the effects of weak microwave irradiation on the spatial orientation and kinetic energy of active site collisions in carnosine, a natural bioactive dipeptide.

Key Findings

• Temperature, microwave intensity, microwave frequency, and microwave polarization mode significantly influence the spatial orientation and kinetic energy of collisions.
• Increased microwave intensity amplifies changes in spatial orientation and kinetic energy, particularly under linear polarization.
• Higher microwave frequencies and temperatures reduce the collision probability and the fraction of high-energy collisions—a reflection of intensified molecular motion.

Conclusion

This study highlights the microwave postpolarization effect (MWPPE), which provides new insights into understanding the molecular mechanisms of nonthermal microwave effects. It also suggests that the orientation and collision dynamics of molecules like carnosine can be manipulated through controlled microwave irradiation, which may have deeper biological and health-related implications, considering the growing concerns about electromagnetic field exposure.