Abstract

Overview

With rising concerns about the health hazards from electromagnetic radiation (EMR), this study primarily aims to explore the carcinogenic potential of 1800 MHz EMR.

Findings

• Exposure duration: Balb/c-3T3 cells were exposed to 1800 MHz EMR for 80 days.
• Increased proliferation: Enhanced Balb/c-3T3 cell proliferation was observed under 1800 MHz exposure.
• No clone formation: No significant clone formation occurred in plate and soft agar assays.
• Enhanced migration: Exposed cells displayed stronger migration abilities than control (Sham) cells.
• mRNA changes: Significant up-regulation in genes related to the cell cycle, cell division, and DNA replication.

Conclusion

The study suggests while 1800 MHz EMR can promote cell proliferation and migration, it did not induce visible malignant transformation though these biological alterations could signal potential health risks by increasing cell proliferation and altering normal cellular functions.