Environmental Factors That Influence Stem Cell Migration: An "Electric Field"

Authors: Iwasa SN, Babona-Pilipos R, Morshead CM

Year: 2017

Category: Cell Biology

Journal: Stem Cells Int.

DOI: 10.1155/2017/4276927

URL: https://www.ncbi.nlm.nih.gov/pubmed/28588621

Abstract

Overview

The review summarizes the influence of electric fields on stem cell migration. The natural movement of cells, known as galvanotaxis, occurs in response to electric potential gradients and is critical during crucial biological processes such as development and wound healing.

Findings

  • Focus on galvanotaxis—the movement of cells along electric potential gradients.
  • Electric fields (EFs) are essential drivers of cell movement in natural settings, heavily involved in developmental processes and healing.
  • Stem cells respond to these electric cues by migrating in a directed manner, potentially aiding in rapid healing and tissue development.

Conclusion

This review provides insights into the mechanisms through which stem cells interpret and respond to electric fields, discussing the potential to harness these processes for regenerative medicine therapies.

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