Weak magnetic fields alter stem cell-mediated growth

Authors: Van Huizen AV, Morton JM, Kinsey LJ, Von Kannon DG, Saad MA, Birkholz TR, Czajka JM, Cyrus J, Barnes FS, Beane WS

Year: 30 Jan 2019

Category: Biophysics

Journal: Science Advances

DOI: 10.1126/sciadv.aau7201

URL: http://advances.sciencemag.org/content/5/1/eaau7201

Abstract

Overview

Biological systems are exposed to electromagnetic fields (EMFs) from both natural sources and technological devices. This study explores the effects of static weak magnetic fields (WMFs; <1 mT) on biological systems, particularly in terms of stem cell behavior and regeneration.

Findings

  • Exposure to WMFs can alter stem cell proliferation and differentiation.
  • Changes are mediated through an increase in reactive oxygen species (ROS) and subsequent expression of heat shock protein 70 (Hsp70).
  • Depending on the strength of the field, WMFs can either increase or decrease tissue formation in vivo.

Conclusion

The study suggests that weak magnetic fields have significant biological effects and could be used therapeutically to manipulate mitotic activity in clinical applications.

electromagnetic fields stem cells reactive oxygen species heat shock protein magnetic field therapy
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