Abstract

Overview

This study delves into the impact of GSM mobile phone electromagnetic radiation (MP-EMR) on the thyroid glands and hormones in the Rattus norvegicus brain, specifically assessing thyroid function, reactive oxygen species (ROS), and monocarboxylate transporter 8 (MCT8) levels.

Methodology

• Experiment involved 40 rats divided into four groups: a control group, and three exposure groups subjected to 120, 150, and 180 minutes of MP-EMR daily.
• Measurements of serum thyroid stimulating hormone (TSH), thyroxine (T4), malondialdehyde (MDA), and MCT8 were conducted using enzyme-linked immunosorbent assay.
• Data analysis was performed using one-way analysis of variance followed by the Duncan test.

Findings

Exposure to MP-EMR resulted in statistically significant reductions in serum TSH and T4 across all exposure groups, with indications of hypothyroidism. Increased MDA and decreased MCT8 levels were noted, particularly at higher durations of exposure (150 and 180 minutes).

Conclusion

Extended exposure to 1800 MHz MP-EMR is linked to significant alterations in the levels of serum TSH, T4, MDA, and MCT8 in Wistar rats, suggesting potential thyroid dysfunction and systemic oxidative stress as a result of prolonged mobile phone radiation exposure.