Acute effects of 2.856 GHz and 1.5 GHz microwaves on spatial memory abilities and CREB-related pathways

Authors: Shengzhi Tan, Hui Wang, Xinping Xu, Li Zhao, Jing Zhang, Ji Dong, Binwei Yao, Haoyu Wang, Yanhui Hao, Hongmei Zhou, Yabing Gao, Ruiyun Peng

Year: 2021 Jun 11

Category: Neuroscience

Journal: Sci Rep

Institution: Sci Rep

DOI: 10.1038/s41598-021-91622-4

URL: https://pubmed.ncbi.nlm.nih.gov/34117282/

Abstract

Overview

This study investigated the acute impacts of 2.856 GHz and 1.5 GHz microwaves on spatial memory and associated molecular pathways in male Wistar rats.

Methodology

  • 120 male Wistar rats divided into four groups: Control, Single Frequency Exposure, Second Frequency Exposure, and Dual Frequency Exposure.
  • Assessment of spatial memory, EEG activity, structural brain injuries, and several molecular markers including p-AKT, p-CaMKII, p-ERK, and p-CREB post-exposure.

Findings

  • Significant declines in spatial memory and alterations in EEG patterns.
  • Differences in molecular expression suggest frequency-specific sensitivities and interactions.
  • Dual frequency exposure led to aggravated molecular downregulations, noting a compounded effect.

Conclusion

The study highlights the significant biological impacts of microwave exposure at different frequencies, suggesting potential health risks and the need for revised safety standards based on both power and frequency of the emission.

microwaves spatial memory CREB pathways EEG molecular pathways
← Back to Stats