900 MHZ electromagnetic field exposure relieved Alzheimer's Disease-like symptoms on APP/PS1 mice

Authors: Zhi W, Zou Y, Ma L, He S, Guo Z, Zhao X, Hu X, Wang L

Year: 2023

Category: Neuroscience

Journal: Biochemical and Biophysical Research Communications

Institution: Biochemical and Biophysical Research Communications

DOI: 10.1016/j.bbrc.2023.03.083

URL: https://www.sciencedirect.com/science/article/pii/S0006291X23003832

Abstract

Overview

Research has increasingly indicated that electromagnetic fields (EMFs), specifically microwaves, could have impactful biological effects on the central nervous system, influencing neurodegenerative conditions such as Alzheimer’s Disease (AD).

Methods

  • Subjects: Amyloid precursor protein (APP/PS1) and WT mice.
  • Exposure: Long-term microwave radiation (900 MHz, SAR 0.25–1.055 W/kg, 2 hours/day for 270 days).
  • Assessments: Behavioral tests and biochemical analysis at multiple intervals.

Findings

The study showed significant cognitive improvements in AD mice subjected to 900 MHz microwave radiation when compared to non-exposed (sham) mice. Notably, this exposure did not induce Aβ plaque formation in WT mice but effectively reduced Aβ accumulation in the brains of APP/PS1 mice. These effects were attributed to various molecular changes, including the modulation of apolipoprotein family member expressions and adjustments in neurotransmitter balance.

Conclusion

Long-term exposure to 900 MHz microwave radiation might retard the progression of Alzheimer's Disease and can benefit in managing AD symptoms. This points towards the potential of microwave EMF therapy in treating AD, which necessitates further exploration considering its implications and the role of EMFs.

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