Exposure to 50 Hz magnetic field at 100 µT exert no DNA damage in cardiomyocytes
Abstract
Overview
The study conducted by Wang et al. investigates the controversial topic of whether electromagnetic fields (EMFs) at city electric frequencies can lead to carcinogenicity and specifically if they affect heart health. The research focuses on exposure to extremely low-frequency magnetic fields (ELF-MFs).
Methodology
Human ventricular cardiomyocytes were exposed to a 50 Hz ELF-MF at 100 µT both continuously for 1 hour and intermittently for 75 minutes. The experiment also included in vivo tests on Sprague-Dawley rats exposed to the same magnetic fields.
Findings
- No DNA damage or cell cycle changes were observed following ELF-MF exposure.
- Redox status and molecular signaling related to DNA damage and stress response (p53 and Rsp70 protein levels) showed no significant alteration.
- These results were consistent in both in vitro and in vivo experiments.
Conclusion
The findings suggest that exposure to 50 Hz magnetic fields at 100 µT may not pose DNA damage risks to cardiomyocytes, thus potentially alleviating some concerns related to the carcinogenic effects of EMFs. However, the conversation and concerns regarding EMFs and public health continue, requiring further detailed and extensive studies.