Abstract

Abstract Summary

Overview

The study examines toxicant-associated fatty liver disease (TAFLD) outcomes when Sprague-Dawley rats are exposed to low doses of aflatoxin B1 (AFB1), both alone and alongside exposure to an extremely low frequency electromagnetic field (ELFEMF).

Findings

• Aflatoxin B1 was tested for its potential to induce TAFLD, which was marked by steatosis and inflammation across both male and female rats.
• Additional observations included increased occurrences of adenomas and other liver neoplastic changes in female rats only.
• There was no amplified effect seen when combining AFB1 with ELFEMF, indicating no additional harm or risk from the EMF in this context.

Conclusion

Exposure to low doses of AFB1 contributes to the development of various liver lesions, including TAFLD. Significantly, the simultaneous exposure to ELFEMF did not exacerbate these effects, offering some insights into the limited immediate interactive influence of electromagnetic fields at low frequencies in this setup.