Non-thermal disruption of β-adrenergic receptor-activated Ca2+ signalling and apoptosis in human ES-derived cardiomyocytes by microwave electric fields at 2.4 GHz
Abstract
Overview
The study delves into the non-thermal effects of 2.4 GHz microwave exposure on human embryonic stem-cell derived cardiomyocytes. This frequency, common in wireless communications like 4G, Bluetooth, and WiFi, is critically evaluated to understand its influence on cellular functionalities and health implications.
Findings
- Non-thermal microwave exposure disrupted normal Ca2+ signaling in response to β-adrenergic receptor (β-AR) activation.
- Such exposure led to spatially-clustered apoptosis, indicating serious implications on cardiomyocyte function and survival.
- The study involved extensive temperature control to isolate non-thermal effects, ensuring that observed outcomes were specifically due to microwave exposure and not thermal factors.
Conclusion
This pivotal research challenges the safety standards concerning non-thermal effects of microwaves, suggesting that existing guidelines might not adequately protect against non-thermal biological disruptions. The findings stress an immediate need for reconsideration of safety limits in light of potential non-thermal health risks.