Spatial memory recovery in Alzheimer's rat model by electromagnetic field exposure

Authors: Akbarnejad Z, Esmaeilpour K, Shabani M, Asadi-Shekaari M, Saeedi-Goraghani M, Ahmadi M.

Year: 2017 Nov 29

Category: Neuroscience

Journal: International Journal of Neuroscience

Institution: Int J Neurosci

DOI: 10.1080/00207454.2017.1411353

URL: https://www.ncbi.nlm.nih.gov/pubmed/29185809

Abstract

Abstract Overview of Spatial Memory Recovery Study

Introduction

Recent studies hint at a significant association between exposure to extremely low frequency electromagnetic fields (ELF-EMFs) and Alzheimer's disease, sparking interest in their potential brain function modulation abilities, particularly in cognitive functions in animal models. This study explores the impact of ELF-EMF exposure on spatial learning and memory in Alzheimer's rat models.

Methods

  • Amyloid-β (Aβ) 1-42 was injected into the lateral ventricle of rats to develop an Alzheimer's disease model.
  • Subjects were divided into six groups, with various combinations of surgical and electromagnetic treatments to assess different aspects of the disease and memory functions.
  • The Morris water maze test was used to evaluate the effects post-ELF-MF exposure.

Findings

The Alzheimer's rat models displayed pronounced impairments in learning and memory functions compared to control groups. Notably, exposure to ELF-MF significantly improved these impairments in two specific groups, suggesting therapeutic potential.

Conclusion

The study concludes that ELF-MF not only mitigates cognitive disorder symptoms in animal models of Alzheimer’s but could possibly interfere with the disease's progression, underscoring the need for further research into electromagnetic field applications in neurodegenerative diseases.

Warning: The research establishes ELF-EMFs as a potential factor in alleviating symptoms of Alzheimer’s, highlighting the need to understand electromagnetic fields’ health implications thoroughly.

← Back to Stats