Abstract

Abstract

Overview

This study investigates the effects of extremely low frequency electromagnetic fields (ELF-EMFs) on cognitive functions in an Alzheimer’s disease rat model, particularly focusing on spatial learning and memory.

Methods

• Amyloid-β (Aβ) 1-42 was injected into the lateral ventricle to establish an Alzheimer’s rat model.
• Rats were divided into six groups with various interventions over 14 days, including control groups, sham surgeries, and magnetic field exposures post Aβ injection.
• Morris water maze tests were used to evaluate the impacts on learning and memory.

Findings

Rats with Alzheimer's showed significant learning and memory impairments. Exposure to ELF-MF improved these impairments in groups that received magnetic fields along with Aβ injection.

Conclusion

Exposure to ELF-MF not only alleviated signs of cognitive disorders in the Alzheimer’s rat model but also appeared to disrupt the formation process of the Alzheimer’s model