Abstract

Overview

Exposure to electromagnetic fields (EMF) and physical stressors like restraint stress (RS) can significantly affect the biological functions and health of organisms. This study investigates the effects on brain lipid compositions in rats subjected to these conditions.

Background

• Exposure to electromagnetic fields (EMF) is a concern for health, affecting tissue and cellular stability.
• Stress affects neuronal responses and brain lipid composition.

Methods

Twenty-four young male Wistar rats were divided into four groups and underwent treatments for 21 days:

• Control
• Restraint Stress (RS)
• ELF-EMF exposure
• Combined RS + ELF-EMF

Post-treatment, various biochemical and neurological analyses were done to measure changes in lipid profiles and peroxidation.

Findings

• Stress and EMF Exposure Increases: Signs of increased stress hormones and changes in lipid concentration were noticeable, particularly with combined RS + ELF-EMF exposure yielding more pronounced effects.
• Lipid Profile Changes: Notable increases in total lipids and cholesterol were detected in certain brain regions due to ELF-EMF. Decreased levels of polar lipids and modifications in fatty acid profiles were also observed.
• Lipid Peroxidation: An increase in lipid peroxidation indicates potential oxidative stress and cellular damage, predominantly in the cortex and cerebellum regions.

Conclusion

Chronic exposure to ELF-EMF presents similarities to physiological stress effects on lipid metabolism in the brain, potentially disturbing cellular balance and emphasizing further implications for health risks associated with EMF exposure.