Abstract

Overview of the Study

Prenatal exposure to radiofrequency electromagnetic fields (RF-EMF) has raised significant concerns regarding its impact on the nervous system.

Objective

The study aims to evaluate the changes in membrane current flow of Purkinje neurons post maternal exposure to 900 MHz pulsed RF-EMF.

Materials and Methods

• Experimental design involved exposure of EMF-exposed group rats to 900 MHz pulsed-EMF radiation for 6 hours daily throughout pregnancy.
• Electrophysiological properties were assessed using whole-cell patch clamp recordings in both current and voltage clamp modes.

Findings

Significant changes were observed in the electrophysiological properties of the cerebellum's Purkinje neurons among male pups:

• Reduction in spontaneous firing rates
• Alteration in the I/V curve characteristics
• Decrease in peak current amplitude

Conclusion

The study concludes that such decrease in neuronal ion conductance following RF-EMF exposure could disrupt normal neurodevelopmental processes.