Biological effects of cell-phone radiofrequency waves exposure on fertilization in mice; an in vivo and in vitro study
Abstract
Overview
The increasing use of cell-phones has been identified as a significant risk factor for population health. This experimental study evaluates the potential effects of cell-phone radiofrequency (RF) waves on fertilization using NMRI mice.
Methodology
- 200 NMRI mice were utilized, divided into control and experimental groups.
- Exposure groups included mice irradiated in "Standby-mode" for 1, 5 and 10 hours daily, and in "Active-mode" for one hour daily.
- Both in vitro and in vivo fertilization parameters were assessed after 30 days of radiation exposure.
Findings
- Significant reductions in two-cell embryos and increases in dead embryos were observed in irradiated groups compared to controls (p = .000).
- A decrease in top-quality (grade-A) embryos was noted, especially with 5-hour daily exposure (p = .015).
- The study recorded an increase in lower-quality (grade-B, C, D) embryos, and changes in pregnancy duration and newborn counts, suggesting an adverse effect on reproductive success.
Conclusion
The study indicates that cell-phone RF exposure detrimentally affects embryo development, reducing the number of newborn mice and altering pregnancy duration, which may lead to fertility failure in NMRI mice.