Abstract

Overview

An electromagnetic field (EMF) is commonly associated with potential health risks, especially in sensitive periods such as pregnancy. This study explores how different conditions of electromagnetic exposure affect androgen synthesis and release in pig endometriums during a crucial developmental window.

Methodology

The study utilized endometrial slices from pigs on days 15-16 of gestation and assessed the effects under various EMF exposures (50 and 120 Hz, for 2 and 4 hours, with and without progesterone supplementation).

Findings

• Key Observations: Progesterone supplementation appeared to mitigate some EMF-induced changes, though its protective efficacy was limited.
• The treatment conditions influenced important hormonal outputs — with noted suppression in testosterone (T) release and an increase in androstenedione (A4) release under certain experimental setups.

Conclusion

The presence and adjustment of frequency and duration of EMF exposure have distinct effects on androgenic activity in gestational endometrial tissue. Progesterone does not fully protect against the modifications induced by EMF radiation, suggesting potential vulnerabilities in reproductive health due to electromagnetic exposures during fetal development.