Abstract

Overview

The study investigates the impact of electromagnetic radiation (EMR), particularly from cell phones, on the reproductive health by analyzing its effects on mouse ovarian follicles during in vitro culture.

Objective

To explore the controversial effects of cell phone EMR on reproduction health, focusing on its role in the ovarian follicle development in mice.

Materials and Methods

• Pre-antral follicles were isolated from young mice and exposed to cell phone in talking mode for 60 minutes.
• Assessment included gelatinolytic activity via zymography and gene expression analysis of MMP-2, MMP-9, TIMP-1, and TIMP-2 using real-time PCR.

Findings

• Murine pre-antral follicle development was significantly affected by cell phone exposure.
• Notable changes in both MMP and TIMP gene expressions were observed.
• Altered gelatinolytic activity in exposed follicles compared to the control group.

Conclusion

Exposure to cell phone radiation demonstrably alters the growth and maturation of murine ovarian follicles, implicating potential reproductive health risks linked with cell phone EMR.