Effect of mobile phone radiation on oxidative stress, inflammatory response, and contextual fear memory in Wistar rat

Authors: Singh KV, Gautam R, Meena R, Nirala JP, Jha SK, Rajamani P

Year: 2020 Mar 24

Category: Environmental Science

Journal: Environ Sci Pollut Res Int

DOI: 10.1007/s11356-020-07916-z

URL: https://www.ncbi.nlm.nih.gov/pubmed/32212071

Abstract

Overview

The study addresses the impacts of continuous exposure to mobile phone radiofrequency electromagnetic field (RF-EMF) radiation on young adult male Wistar rats, exploring effects on the brain and specific responses in the hippocampus area.

Methodology & Exposure

For 16 weeks, subjects were exposed daily to 1966.1 MHz frequency and 4.0 mW/cm2 power density RF-EMF radiation. The research measured various physiological and biochemical markers including oxidative stress and pro-inflammatory cytokines.

Findings

  • Significant increase in hippocampal oxidative stress.
  • Rise in levels of pro-inflammatory cytokines such as IL-1beta, IL-6, and TNF-alpha.
  • Increased adrenal gland weight and stress hormones including ACTH and corticosterone.

Conclusion

Chronically exposing Wistar rats to MP-RF-EMF radiation from mobile phones can lead to considerable increases in oxidative stress and inflammation, along with deregulation of HPA axis hormones. It highlights potential health risks associated with prolonged mobile phone usage.

mobile phone radiation oxidative stress inflammation hippocampal function Wistar rat electromagnetic fields health risks
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