Effect of mobile phone signal radiation on epigenetic modulation in the hippocampus of Wistar rat

Abstract

Overview

Concerns about the health risks associated with mobile phone radiation have been growing due to its exponential increase in use. Notably, the U.S. National Toxicology Program highlighted potential health hazards from cell phone radiation exposure in 2018.

Findings

This study explores the dose-dependent and frequency-dependent impacts of mobile phone signal radiation on DNA and Histone methylation in the hippocampus of Wistar rats. Using a rigorous experimental setup, researchers divided 96 male Wistar rats into 12 groups, exposing them to frequencies of 900 MHz, 1800 MHz, and 2450 MHz. Over varying durations (1, 3, and 6 months), significant epigenetic modulations—decreased DNA methylation and increased histone methylation—were observed in the rat's hippocampus. Gene expression changes were evident due to these modulations.

Conclusion

The findings demonstrate that microwave exposure from mobile phones does indeed lead to significant and concerning changes in epigenetic markers in the brain, especially with prolonged exposure.