Proteomic impacts of electromagnetic fields on the male reproductive system

Authors: Sepehrimanesh, M. & Davis, D.L.

Year: 2016

Category: Proteomics

Journal: Comp Clin Pathol

DOI: 10.1007/s00580-016-2342-x

URL: http://link.springer.com/article/10.1007%2Fs00580-016-2342-x

Abstract

Overview

The prevalence of mobile phone use is climbing globally, paralleled by an observed increase in infertility rates across various nations. Parallel investigations in infertility clinics from Australia, India, the USA, and Iran suggest a potential link between extensive mobile phone usage and decreased sperm quality.

Findings

  • Exposure to electromagnetic fields (EMF), whether from mobile phones or simulated sources, has been shown to disrupt sperm structure and function, leading to decreased sperm quantity.
  • Proteomic analyses indicate significant changes in the protein expression related to DNA and cellular functions critical for male fertility, highlighting EMF's role as a potential male-mediated teratogen.
  • The field of proteomics provides a detailed and complex understanding of protein functions within biological systems, critical for understanding the pathways from DNA transcription to protein translation affected by EMF.

Conclusion

This review synthesizes clinical and experimental proteomic data to support the thesis that EMF exposure is potentially harmful to male reproductive health, emphasizing its role in contributing to increased infertility rates.

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