Abstract

Overview

The study investigates the impact of microwave radiation (MWR) on rats, particularly focusing on oxidative stress and neurogeneration. The research used Wistar rats, subjected to a frequency of 2100MHz for extensive periods to simulate chronic exposure conditions.

Key Findings

• Oxidative Stress: Exposure to 2100 MHz frequency significantly altered glutathione homeostasis, leading to increased oxidative stress.
• Inflammation and Demyelination: Activated inflammatory responses were observed, coupled with notable alterations in cytokine levels. Histopathological and electron microscopic assessments revealed changes in myelination and brain cellular organelles.
• Mitochondrial Damage and Organ Degeneration: The exposed rats showed degeneration in critical brain regions like the hippocampus, cerebellum, and corpus callosum, as well as mitochondrial damages.

Conclusion

The findings amplify concerns about the health risks associated with MWR, suggesting that chronic exposure is likely to cause significant neural damage through a series of biochemical changes, ultimately promoting neurodegenerative diseases.