The inverse relation between mitochondrial transmembrane potential and proteins α-helix in neuronal-like cells under static magnetic field and the role of VDAC

Authors: Calabrò E, Magazù S, Currò M, Ientile R

Year: 2020 Mar 9

Category: Biomedicine

Journal: Electromagn Biol Med

DOI: 10.1080/15368378.2020.1737808

URL: https://www.ncbi.nlm.nih.gov/pubmed/32149540

Abstract

Overview

In this study, the interaction between static magnetic fields and neuronal-like cells was explored, focusing on cellular and molecular changes.

Findings

  • Exposure durations were 3, 7, 15, and 24 hours to a magnetic field intensity of 2 mT.
  • Methods used include Fourier Transform Infrared (FTIR) Spectroscopy for protein structure analysis and fluorescence techniques for measuring mitochondrial transmembrane potential.
  • A significant inverse relation was found between mitochondrial transmembrane potential and the intensity of the Amide I band, correlating with time exposure.

Conclusion

This significant discovery highlights the potential influence of magnetic fields on mitochondria-related cellular mechanisms. These mechanisms could link to serious health issues such as cancer and neurodegenerative diseases, emphasizing the critical need for further study and awareness of EMF exposure.

mitochondrial transmembrane potential static magnetic field neuronal-like cells VDAC neurodegeneration cancer protein structure
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