Effect of electromagnetic radiation on redox status, acetylcholine esterase activity and cellular damage contributing to the diminution of the brain working memory in rats

Authors: Sharma S, Shukla S

Year: 2020 Mar 20

Category: Neuroscience

Journal: J Chem Neuroanat

DOI: 10.1016/j.jchemneu.2020.101784

URL: https://www.ncbi.nlm.nih.gov/pubmed/32205214

Abstract

Overview

The study investigates the profound impact of electromagnetic radiation (EMR) emitted from mobile phones on behavioral and cognitive functions in rats, focusing on biochemical and cellular alterations in the brain.

Methodology

This research was conducted on 24 male Wistar rats divided randomly into four groups, with each group receiving varying durations of EMR exposure—1 hour, 2 hours, and 4 hours over a period of 90 days. A control group was included for baseline measurements.

Findings

  • Increased malondialdehyde levels indicating oxidative stress driven by mobile radiation.
  • Significant depletion in critical antioxidants such as superoxide dismutase, catalase, and other redox enzymes.
  • Decreased acetylcholinesterase levels suggesting altered neurotransmission.
  • Notable cellular degeneration within the hippocampus.

Conclusion

The findings elucidate that prolonged exposure to microwave radiation from mobile phones noticeably diminishes brain working memory, presumably through oxidative stress and neural damage. These alterations may explain the observed behavioral changes and cognitive decline.

electromagnetic radiation redox status acetylcholinesterase activity cellular damage cognitive alterations
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