Neuroprotective Efficacy of Luteolin on a 900-MHz Electromagnetic Field-Induced Cerebellar Alteration in Adult Male Rat
Abstract
Abstract Summary
Overview
The rising awareness regarding the adverse health effects of electromagnetic fields (EMFs) from cell phones has led to globally increasing concerns. This study is pertinent as it focuses on a frequently used GSM frequency.
Findings
- The research aimed to explore the harmful effects of 900 MHz EMF exposure for one hour per day on the cerebella in 12-week-old male Wistar albino rats.
- The study evaluated the neuroprotective role of luteolin, a compound administered at 20 μg/kg/day.
- Biological changes were observed through serological, biochemical, and histopathological assessments.
- Significant findings include increased oxidative stress markers and decreased total counts of neural cells in EMF exposed groups, alongside observed cerebellar tissue damage.
- Conversely, luteolin treatment showed potential neuroprotective effects by reducing oxidative stress and mitigating EMF-induced cellular damage.
Conclusion
The findings emphasize a critical health implication of cellphone-related EMF exposure that could harm cerebellar function, possibly mitigated by antioxidants like luteolin.