Abstract

Overview

This study meticulously explores the implications of Radiofrequency Electromagnetic Radiation (RFEMR) on adolescent rats, focusing particularly on amygdala morphology and associated behavior changes.

Findings

• Exposure Settings: Adolescent male albino Wistar rats were exposed to 900 MHz from a mobile phone at a power density of 146.60 μW/cm2 in silent-mode for 28 days.
• Morphological Changes: Cellular architecture of the rat amygdala was notably perturbed with a significant reduction in the number of healthy neurons specifically in the basolateral and cortical nuclei, and evident dendritic arborization.
• Behavioral Alterations: These structural changes were accompanied by altered place preference behavior, exhibiting signs of hyperactivity-like behavior. However, the brain caspase-3 activity showed no change post-exposure.

Conclusion

Chronic RF-EMR exposure severely affects the amygdala structure and alters typical behavior in rats, highlighting potential risks that such exposures could pose on brain health and behavior.