Abstract

Overview of the Study

This study aims to explore the biochemical and pathological impacts of continuous exposure to a 900-megahertz (MHz) electromagnetic field (EMF) on male rat kidney and bladder tissues during postnatal days 22 to 59.

Methods Employed

• Participants: 24 male Sprague Dawley rats, 21 days old, divided into Control (CG), Sham (SG), and EMF Groups (EMFG).
• Procedures:
  • CG received no procedure.
  • SG was caged without EMF exposure for 1 hour daily.
  • EMFG was exposed to continuous 900-MHz EMF for 1 hour daily under same conditions as SG.
• Analysis Methods: Post-sacifice histomorphological evaluation using H&E and Masson trichrome stains, TUNEL method for apoptosis, TEM for kidney tissue, and analysis of oxidant/antioxidant parameters.

Key Findings

The exposure notably induced:

• Increase in tissue malondialdehyde levels in both kidney and bladder tissues in EMFG
• Decrease in catalase and glutathione levels in EMFG
• Pathological changes including tubule dilatation, vacuolization, and increased apoptosis in kidney and bladder tissues

Conclusion

The study concludes that continuous exposure to 900-MHz EMF significantly increases oxidative stress and induces several pathological alterations in the tissues studied, reinforcing the health risk concerns associated with EMF exposure.