Abstract

Overview

The increasing use of mobile phones has raised concerns about the potential biological effects of electromagnetic radiations emitted. Specifically, this study explores how these radiations at 1800 MHz frequency impact the parotid gland, which is in close contact with mobile phones during use.

Methodology

• Three groups of Sprague-Dawley Albino rats (21 total) were used, exposed to zero (control), 6 hours, and 12 hours of electromagnetic fields daily for 30 days.
• Evaluation of the gland involved histopathological and immunohistochemical methods.
• Biochemical analysis of antioxidant and oxidant levels in the parotid tissue was also performed.

Findings

• Significant degenerative changes in parotid tissue were observed with increased exposure.
• Rats exposed to longer durations showed a higher apoptotic index.
• Intranuclear inclusions were also noted during electron microscopy examinations.

Conclusion

This experimental study confirmed that prolonged exposure to an 1800 MHz electromagnetic field has adverse histopathological and biochemical effects on the parotid gland in rats. The findings suggest a need for further research into this topic and potential revisions in mobile phone use guidelines.