Prenatal Effects of a 1,800-MHz Electromagnetic Field on Rat Livers

Authors: Tumkaya L, Yilmaz A, Akyildiz K, Mercantepe T, Yazici ZA, Yilmaz H.

Year: 2019 Dec 4

Category: Biomedical Research

Journal: Cells Tissues Organs

Institution: Cells Tissues Organs

DOI: 10.1159/000504506

URL: https://www.ncbi.nlm.nih.gov/pubmed/31801129

Abstract

Overview

The prevalence of devices emitting electromagnetic fields (EMF), like mobile phones, is increasing, and their potential harmful biological impacts are of significant concern. This study investigates the biochemical and histological changes in rat livers due to prenatal exposure to 1800 MHz EMF.

Findings

  • Rats were grouped and exposed to 1800-MHz EMF for 6, 12, or 24 hours daily during uteroplacental life, with corresponding controls unexposed.
  • Significant increases in malondialdehyde levels and reductions in glutathione levels were observed in EMF-exposed rats compared to controls.
  • Liver function markers like Serum Ca2+, alanine transaminase, and aspartate aminotransferase levels were elevated in exposed groups.
  • Histologically, exposed livers showed considerable hepatocyte vacuolation and degeneration, eosinophilic staining of hepatocytes, and loss of cellular membrane integrity.

Conclusion

Prenatal exposure to EMF caused persistent liver damage into puberty in rats, indicating significant concerns for potential health risks.

EMF prenatal exposure rat study liver damage biochemical analysis histological effects
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