Abstract

Overview

The study investigates the physiopathological effects of electromagnetic fields (EMF) emanating from 4.5 G mobile phone radiation on rat liver tissues, and the potential mitigating impact of quercetin, an antioxidant.

Methods

• Male Wistar-Albino rats were distributed into four groups, with eight rats in each.
• The groups included a control group, a sham group, an EMF exposed group, and an EMF with quercetin treatment group.
• Liver tissues were extracted post 30 days for histopathological and immunohistochemical assessments.

Findings

In the EMF exposed group:

• Significant liver tissue damage evidenced by dilatation of sinusitis, higher than in the sham group.
• Higher levels of caspase-3 and TNF-α immunopositive cells, indicating inflammation and cellular apoptosis.
• Increased malondialdehyde level signalling elevated oxidative stress, although antioxidant enzyme levels did not show significant difference.

Conclusion

Exposure to 2600 MHz EMF from 4.5 G mobile phones significantly damages liver tissues. Moreover, the application of 100 mg/kg/day quercetin was unable to fully counteract these effects, suggesting a potent health risk from such EMF exposures.