Oxidative damage in the liver and brain of the rats exposed to frequency-dependent radiofrequency electromagnetic exposure: Biochemical and histopathological evidence

Authors: Anjali Sharma, Sadhana Shrivastava, Sangeeta Shukla

Year: 2021 Aug 17

Category: Toxicology

Journal: Free Radic Res

DOI: 10.1080/10715762.2021.1966001

URL: https://pubmed.ncbi.nlm.nih.gov/34404322/

Abstract

Overview

The study investigates the oxidative damage in liver and brain tissues in rats subjected to frequency-dependent radiofrequency electromagnetic radiation (RF-EMR) to explore the potential health hazards of EMR exposure.

Methodology

  • 40 Wistar rats divided into control and EMR exposed groups.
  • Exposed to frequencies of 900, 1800, and 2100 MHz.
  • Specific absorption rates (SAR) noted as 0.434, 0.433, and 0.453 W/kg respectively.
  • Exposure duration set at 1 hour/day, 5 days/week for 1 month.

Findings

  • Significant changes in body weight, hematologic parameters, and serum biochemistry.
  • Increase in lipid peroxidation and decrease in acetylcholinesterase activity, indicating severe biochemical alterations.
  • Distinct degenerative changes in liver and brain histopathology.

Conclusion

RF-EMR exposure leads to notable oxidative damage, particularly in the brain, affirming the critical impacts of EMR on biological tissues.

EMR toxicity oxidative damage liver damage brain damage rat study radiofrequency electromagnetic exposure biochemical evidence
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