Pathological Findings Observed in Kidneys of Postnatal Male Rats Exposed to 2100 MHz EMF

Authors: Bedir R, Tumkaya L, Mercantepe T, Yilmaz A

Year: 2018 Dec 29

Category: Medical Research

Journal: Arch Med Res

Institution: Arch Med Res

DOI: 10.1016/j.arcmed.2018.12.010

URL: https://www.ncbi.nlm.nih.gov/pubmed/30600117

Abstract

Overview

The increasing exposure of young individuals to electromagnetic fields (EMF) due to the use of modern communication devices such as mobile phones poses potential health risks. This study examines the impact of long-term exposure to an EMF of 2100 MHz on kidney health in rats.

Materials and Methods

  • Sample: Twenty-four Sprague Dawley rats divided into three groups—control (no exposure), exposure to 2100 MHz for 6 hours/day, and exposure for 12 hours/day, all for 30 days.
  • Techniques: Immunohistochemical analysis for apoptosis evaluation and biochemical tests for oxidative stress indicators.

Findings

  • Deterioration in the brush border in renal tubules.
  • Increased apoptosis in kidney cells as indicated by positive caspase-3 staining in EMF-exposed groups.
  • Increase in renal malondialdehyde (MDA) levels and decrease in glutathione (GSH) levels compared to the control group, indicating oxidative stress.

Conclusion

Exposure to 2100 MHz EMF induces oxidative stress-mediated acute renal injury in rats, which is dependent on the duration and intensity of exposure. This study highlights the potential health risk of long-term EMF exposure in similar biological conditions.

EMF kidney health oxidative stress apoptosis rat model mobile phone radiation
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