Evaluation of oxidative injury in sciatic nerves of male rats exposed to continuous 900-MHz EMF throughout adolescence

Authors: Kerimoğlu G, Güney C, Ersöz Ş, Odacı E

Year: 2018 Jan 10

Category: Neuroscience

Journal: J Chem Neuroanat

DOI: 10.1016/j.jchemneu.2018.01.001

URL: https://www.ncbi.nlm.nih.gov/pubmed/29331319

Abstract

Overview

The increasing concerns regarding the effects of electromagnetic fields (EMFs) emitted by mobile phones, especially given their widespread use among the nearly 7 billion people globally, highlights the need for detailed scientific study. Young adolescents, who frequently use mobile phones and carry them in their pockets or bags, may be at significant risk of developing health issues related to EMF exposure.

Study Purpose

This study aimed to investigate if the continuous exposure to 900-MHz EMF affects the sciatic nerve in male rats during their adolescence, a critical developmental period.

Methodology

  • Subjects: 24 male Sprague Dawley rats divided into Control, Sham, and EMF exposure groups.
  • Exposure: The EMF group was exposed to a 900-MHz EMF for 1 hour daily from postnatal day 21 to 59.
  • Analysis: Post-exposure, sciatic nerve samples were biochemically and histopathologically evaluated.

Findings

Results indicated significant changes in the EMF exposed group:

  • Increased levels of biochemical markers such as Malondialdehyde (MDA), Superoxide Dismutase (SOD), and Catalase (CAT).
  • Noticeable thickening in the epineurium of sciatic nerves.
  • A higher apoptotic index suggesting more cell death.

Conclusion

Continuous exposure to 900-MHz EMF during adolescence significantly increases oxidative stress and cellular changes in the sciatic nerve, indicating potential harmful effects that require further investigation and awareness.

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