Alterations of thymic morphology and antioxidant biomarkers in male rats following exposure to continuous 900 MHz EMF during adolescence

Abstract

Overview

This study explores the impact of a 900 MHz electromagnetic field (EMF) exposure on thymic tissue morphology and antioxidant levels in male rats. Throughout adolescence, specific focus is placed on critical developmental periods.

Methodology

• Three groups of six 21-day-old male Sprague-Dawley rats were used: control, sham, and EMF.
• The EMF group was exposed to 900 MHz EMF for 1 hour daily from postnatal day 22 to 59.
• Rats were sacrificed on postnatal day 60 for analysis.

Findings

Histological assessments and biochemical analysis revealed significant alterations due to EMF exposure:

• Increased Malondialdehyde (MDA) levels: This indicates higher oxidative stress in the EMF-exposed group compared to controls.
• Structural changes: The presence of extravascular erythrocytes was noted in medullary and corticomedullary regions of the thymus in EMF group.

Conclusion

The study highlights that exposure to 900 MHz EMF during adolescence may lead to oxidative stress and structural changes in the thymic tissue of male rats, indicating potential health risks associated with EMF exposure during formative years.