Effects of Combined Exposure to Microwave and Heat on Gene Expression and Sperm Parameters in Mice

Authors: Gohari FA, Saranjam B, Asgari M, Omidi L, Ekrami H, Moussavi-Najarkola SA

Year: 2017 Apr-Jun

Category: Experimental Biology

Journal: J Hum Reprod Sci

Institution: School of Public Health

DOI: 10.4103/jhrs.JHRS_136_16

URL: https://www.ncbi.nlm.nih.gov/pubmed/28904503

Abstract

Study Summary

Overview

This experimental animal study aimed to assess the effects of exposure to microwaves (MWs) and heat on gene expression and sperm parameters in mice. Specifically, the study explores the ramifications of combined and separate exposures to 900-MHz MW radiation (typical of cell phone radiation) and high-temperature environments.

Methodology

The research involved 12 male mice, which were divided into four distinct groups:

  • Control group: no exposure.
  • Test group 1: exposed to 900-MHz MW.
  • Test group 2: exposed to a hot and sultry climate.
  • Test group 3: exposed simultaneously to 900-MHz MW and high heat.

In each group, gene expression and sperm parameters were meticulously measured.

Findings

The study revealed that:

  • All test groups maintained the integrity of the seminiferous tubule and germ line cells.
  • A significant increase in the number of dead sperms was noted in mice exposed separately to heat compared to other groups (P < 0.05).
  • The combined exposure group showed an elevated ratio of Bax expression (0.015 ± 0.006).

Conclusion

The findings indicate that both separate and combined exposures to microwaves and high temperatures can adversely affect sperm parameters and gene expression in male mice. This raises concerns about the potential health risks associated with exposure to cell phone radiation and high environmental temperatures.

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