Abstract

Overview

The increasing use of electromagnetic field-emitting devices raises significant concerns regarding their effects on human health, particularly on stress-related hormones.

Objective

The study focuses on the long-term impacts of mobile radiofrequency (RF) at 900 MHz on adrenal gland pathophysiology and the hormonal balance in male Wistar rats.

Materials and Methods

• Subject Group: Adult male Wistar rats
• Exposure: 6 hours daily to mobile RF for 4-8 weeks
• Controls: Intact and devices switched-off
• Measurements: ELISA method for plasma ACTH and cortisol levels
• Histological Analysis: Hematoxylin and eosin staining on adrenal gland and brain tissues

Findings

Significant findings include:

• Increased Levels: Elevated plasma ACTH and cortisol after prolonged RF exposure.
• Adrenal Gland Changes: Thickening of the adrenal cortex's fasciculata layer, with an increase in cell size and perimeter.
• Brain Tissue Impact: Noticeable vacuolization with an increase in both the number and size of vacuoles in brain tissue.

Conclusion

Prolonged exposure to cell phone RF induced significant hormonal changes and structural alterations in the adrenal gland and brain. Public awareness and exposure reduction are advised.