Cell phone radiation changes corticotrophin hormone levels & histology of brain and adrenal glands in male rats

Abstract

Overview

Electromagnetic field-emitting devices such as cell phones are prevalently used, raising concerns about potential health risks linked to mobile radiofrequency (RF) radiation, specifically regarding stress hormones and adrenal gland function.

Materials and Methods

• Male Wistar rats were exposed to mobile RF900 MHz for 6 hours daily over 4-8 weeks, with comparisons made against both intact and switched-off exposed control groups.
• Plasma ACTH (adrenocorticotrophic hormone) and cortisol levels were quantified using the ELISA technique.
• Histological examinations were performed on adrenal gland and brain tissues, including measurements of fasciculate layer thickness, cell count, and perimeter in the adrenal gland using Fiji software.

Findings

• Significant increases in plasma ACTH and cortisol levels were noted following prolonged RF exposure.
• Changes in adrenal gland structure included thickening of the fasciculata layer and increase in cell size and perimeter, despite a constant cell count.
• Increased vacuolization was observed in the brain tissue, with a noticeable rise in the number and size of vacuoles over the two-month exposure period.

Conclusion

The study highlights significant endocrine and structural alterations in the adrenal gland and brain following extended exposure to cell phone RF, emphasizing the need for public awareness and minimized exposure to potentially harmful RF radiation.