Abstract

Abstract

Overview

The study investigates the effects of prenatal exposure to Wi-Fi (2.4 GHz) signals on the placenta. The placenta plays a crucial role by supplying nutrients and oxygen to embryos and removing waste products.

Materials and Methods

• Pregnant mice were exposed to Wi-Fi signal (2.4 GHz) for durations of 2 and 4 hours.
• Placenta tissues were harvested to measure MDA and SOD levels through assays and real-time PCR analysis.
• Apoptosis in placenta tissues was assessed using the TUNEL assay.
• Data were analyzed using one-way ANOVA with Prism version 6.0 software.

Findings

Significant increases were observed in:

• MDA and SOD levels in groups exposed to Wi-Fi signals.
• SOD mRNA expression through quantitative PCR in Wi-Fi exposed groups.
• Expressions of CDKN1A and GADD45a genes.
• Apoptosis rates in placenta tissues.

Conclusion

The findings suggest that Wi-Fi signals can increase lipid peroxidation, SOD activity, apoptosis, and overexpression of CDKN1A and GADD45a in mouse placenta tissues. Further research is needed to explore additional genes and pregnancy aspects to better understand the impact of Wi-Fi radiation on fertility and pregnancy outcomes.