Abstract

Overview

DNA repair processes are vital for maintaining genomic stability. This study investigates the effects of magnetic fields (MF) on DNA repair mechanisms, specifically DNA double strand breaks (DSBs) in Saccharomyces cerevisiae.

Findings

• Exposure conditions included a 50Hz, 2.45mT sinusoidal MF, with Helmholtz coils generating the field.
• DSBs were induced in yeast cells using HO endonuclease and studied over a period of 21 days.
• A significant increase in colony formation and DNA repair activity was observed under MF exposure. Increased reparation rates varied significantly between different strains.

Conclusion

Long-term exposure to low frequency magnetic fields may enhance the efficiency of DNA repair, suggesting a possible interaction between electromagnetic fields and genetic stability. This indicates a need for continued investigation into the implications of MF exposure on health.